“Curls over curls, there is the door to all wonders!” – Lao Zi (Dao De Jing)•Discover why the ancient Chinese Rivermaps may be the schematics of DNA.•Discover the Diagrams of Changes as BCC, FCC, Double Helix and more.•Discover the secrets behind twists and double helix.•Discover DAO, the Curling Universe described by Lao Zi.•Discover Prenatal Trigrams and the basis of Yi Jing (or I Ching).•Discover how a stable structure may be formed from free energies.•Discover how we may live simply and happily in this Curling Universe.